Sometimes in Chrome, I try to scroll down and I end up going back. This is the single most annoying thing that happens to me when I'm using chrome. Fortunately you can disable this.
Disable it only for a specific application
To disable it for Chrome, open up a terminal and execute:
defaults write com.google.Chrome AppleEnableSwipeNavigateWithScrolls -bool FALSE
Similarly you can disable it for any app, just replace com.google.Chrome with whatever app you want this gesture disabled on.
Disable it system wide
System Preferences -> Trackpad -> More Gestures. And then untick
Swipe between pages